Table 4.
Levels of α1b ADR mRNA in hippocampal subfields after bilateral ADX with low (10 mg) or high (50 mg) corticosterone replacement or SHAM surgery
| Group | α1b ADR mRNA: % Integrated density w.r.t. SHAM | n | ||
|---|---|---|---|---|
| CA1 | CA3 | Dentate gyrus | ||
| Naive | 89 ± 11 | 91 ± 5 | 85 ± 8 | 6 |
| SHAM | 100 ± 11 | 100 ± 11 | 100 ± 8 | 6 |
| ADX | 102 ± 6 | 88 ± 8 | 97 ± 8 | 5 |
| ADX + 10 mg | 107 ± 9 | 104 ± 9 | 108 ± 5 | 6 |
| ADX + 50 mg | 109 ± 13 | 101 ± 11 | 95 ± 2 | 6 |
A naive group was also included that did not undergo any experimental manipulation. Data are expressed as mean percentage of integrated density ± SEM with respect to (w.r.t.) SHAM group. There were no significant differences between groups as determined by one-way ANOVA.