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. 1999 Oct 1;19(19):8435–8442. doi: 10.1523/JNEUROSCI.19-19-08435.1999

Fig. 7.

Fig. 7.

Notch staining is increased in the cytoplasm ofDps-overexpressing cells. The distribution of Notch and Dps in third instar larval wing disks is shown. a, In wild-type disks, Dps protein is expressed at very low levels.b, Notch is expressed ubiquitously throughout the larval wing disk. c, d, Dps protein can be induced in wing (thinarrow) and haltere (thickarrow) disks using apnr-GAL4 line to drive expression of UAS-Dps in transgenic lines (c). Notch protein specifically accumulates in cells overexpressing Dps (d).e, f,cut-GAL4 was used to overexpressDps at the developing wing margin. Note the high levels of Dps protein that accumulate in the cytoplasm of cells at the wing margin (e, arrow). Overexpression ofDps at the margin causes Notch to accumulate within the cytoplasm of these cells (f, arrow).g, h, Overexpression of Dps in a subset of neurons within the developing eye disk (g, arrow) also causes increases in Notch expression within the cytoplasm of these cells (h, arrow).