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. 1999 Jul 15;19(14):6068–6078. doi: 10.1523/JNEUROSCI.19-14-06068.1999

Fig. 4.

Fig. 4.

A trap vector was inserted in the Psa gene.A, The schema for wild and trapped alleles.a, Wild-type allele; b, trapped allele.Bold bar (psa-2) represents the probe for Southern blot analysis that recognizes an EcoRI fragment of ∼15 kb from the wild allele and a 3.8 kb fragment from the trapped allele.Open squares represent exons of the Psa gene.B, Examples of Southern blot analyses of the genotypes.Lanes 1–11, Results of individual mice. Genotype and sex are shown at the top of each lane. W, Wild-type mouse; Ht, heterozygote; Hm, homozygote; M, male; F, female.