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Activity in the open field of wild-type and 5-HT1B KO mice in the single-session exploration test. A, Locomotor activity as measured by the mean (±SE) distance run (centimeters) in fast movements. B, Thigmotaxis as measured by the mean (±SE) time spent (seconds) at periphery.C, Object exploratory activity as measured by the mean (±SE) time spent (seconds) at the object area. *Statistically significant (wild type vs 5-HT1B KO; p < 0.05).
