Table 1.
Mapping the murine gustducin promoter
| Transgene | Transgenics generated | Transgenics showing taste cell expression1-a | Transgenics showing non-taste cell expression1-a |
|---|---|---|---|
| GUS1.4-lacZ | 7 G0s generated | 0/7 | 0/7 |
| 4 lines tested | |||
| 3 G0s tested | |||
| GUS(1.4+2.5)-lacZ | 7 G0s generated | 3/51-b | 2/5 |
| 2 lines tested | variable penetrance1-c | retinal interneurons | |
| 3 G0s tested | variable expression1-d | ||
| GUS(1.4+2.5rev)-lacZ | 3 G0s generated | 1/3 | 1/3 |
| 3 lines tested | variable penetrance1-c | retinal interneurons | |
| variable expression1-d | |||
| GUS2.5-hsp68-lacZ | 3 G0s generated | 0/3 | 3/3 |
| 3 lines tested | tongue muscle | ||
| GUS5.9-lacZ | 3 G0s generated | 0/3 | 2/3 |
| 2 lines tested | taste bud-associated cells | ||
| 1 G0 tested | |||
| GUS8.4-lacZ | 7 G0s generated | 7/7 | 2/7 |
| 5 lines tested | uniformly high levels | retinal neurons | |
| 2 G0s tested |
β-Galactosidase expression scored by immunofluorescence and/or histochemistry.
Two lines and one G0 mouse tested.
Relative number of β-galactosidase-positive taste cells versus GUS8.4-lacZ mice.
Relative level of β-galactosidase expression versus GUS8.4-lacZ mice.