Table 3.
Multivariate analysis of OS in the patients.
Variables | OS |
|
---|---|---|
HR (95%CI) | P-value | |
EGFL7 (high vs. Low) | 2.307 (1.151–4.625) | .019 |
Age (≥60 vs. <60 years) | 1.229 (0.614–2.459) | .560 |
WBC (≥15 vs. <15 × 109/L) | 1.325 (0.674–2.602) | .415 |
BM blasts (≥70 vs. <70%) | 0.833 (0.419–1.659) | .604 |
PB blasts (≥20 vs. <20%) | 1.589 (0.753–3.354) | .224 |
FLT3-ITD (positive vs. negative) | 2.406 (1.086–5.329) | .031 |
NPM1 (mutated vs. wild) | 1.388 (0.562–3.430) | .477 |
DNMT3A (mutated vs. wild) | 1.158 (0.562–2.383) | .691 |
RUNX1 (mutated vs. wild) | 3.165 (1.332–7.521) | .009 |
TP53 (mutated vs. wild) | 12.175 (3.161–46.895) | .000 |
MLL-PTD (positive vs. negative) | 2.425 (0.776–7.577) | .128 |
Abbreviations: OS, Overall survival; HR, hazard ratio; CI, confidence interval; WBC, white blood cell; BM, bone marrow; PB, peripheral blood.