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. 2019 Jul 16;20(10):1319–1327. doi: 10.1080/15384047.2019.1638670

Table 1.

Functional classification of the 64 genes used for targeted sequencing.

Functional classification Genes
Oncogenes BRAF, FYN, KIT, KRAS, MET, MFHAS1, MYC, NRAS, PDGFRA, PIM1, SPI1
Anti-oncogene AIM1, PRDM1, PTEN, ST5, TP53
Apoptosis BCL2, CARD11, FAS, TNFAIP3, TNFRSF14
Cell cycle CCND1, CDKN2A, CDKN2B, XPO1
Immune response CD58, CD79A, CD79B, CXCR4, IGHD, IGHJ, KIR2DL4, KIR3DL2
Transcriptional regulation BCL6, ID3, IRF4, TCF3, DDX3X
DNA methylation DNMT3A, DNMT3B, TET2
Histone acetylation BCOR, CREBBP, EP300
Histone methylation KMT2D, EZH2
Signaling pathways NOTCH1, NOTCH2, STAT3, STAT6, CTNNB1, SOCS1, GNA13
Receptor tyrosine kinase ALK
Autophagy ATG5
Homeostasis FOXO1, FOXO3
Others IDH2, ITPKB, MEF2B, MYD88, RHOA, B2M, CIITA