Table 2.
Chi-square analysis of mutated genes in patients with ENKTL (both nasal and extra-nasal), ANKL and EBV+TL.
| Gene | ENKTLs | ANKLs | EBV+TLs |
P 1 |
P 2 |
|---|---|---|---|---|---|
| (ENKTL vs ANKL) | (ENKTL vs EBV+TL) | ||||
| STAT3 | 33 | 2 | 5 | 0.763 | 0.144 |
| KMT2D | 23 | 3 | 6 | 0.885 | 0.889 |
| DDX3X | 25 | 3 | 3 | 0.993 | 0.121 |
| TET2 | 15 | 2 | 2 | 1.000 | 0.461 |
| EP300 | 14 | 0 | 4 | 0.460 | 1.000 |
| NOTCH1 | 12 | 3 | 3 | 0.262 | 1.000 |
| BCOR | 13 | 3 | 1 | 0.313 | 0.298 |
| CIITA | 12 | 1 | 2 | 1.000 | 0.718 |
| TP53 | 11 | 1 | 1 | 1.000 | 0.423 |
| MFHAS1 | 5 | 0 | 5 | 1.000 | 0.025 |
| ITPKB | 4 | 3 | 3 | 0.010 | 0.356 |
| PRDM1 | 7 | 0 | 1 | 0.868 | 0.838 |
| NOTCH2 | 5 | 0 | 3 | 1.000 | 0.499 |
| ALK | 4 | 2 | 1 | 0.156 | 1.000 |
| EZH2 | 5 | 2 | 0 | 0.231 | 0.520 |
| CDKN2A | 1 | 3 | 0 | ＜0.001 | 1.000 |
| MEF2B | 2 | 2 | 0 | 0.041 | 1.000 |
| SOCS1 | 2 | 2 | 2 | 0.041 | 0.436 |
| NRAS | 1 | 2 | 0 | 0.011 | 1.000 |