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. 2019 Sep 25;8:e47534. doi: 10.7554/eLife.47534

Table 4. HPRT kinetic parameters.

HPRT Km (guanine)
(μM)
Km (PRPP)
(μM)
kcat
(s−1)
B. anthracis 1 5.2 ± 1.8 111.6 ± 16.8 22
B. subtilis -- 165.6 ± 11.9 25.4
C. burnetii 17.6 ± 2.0 44 ± 3.3 12.9
P. phosphoreum -- 81 ± 12.5a 30.4a
N. meningitidis 68 ± 7.0 103 ± 12 9.6
E. colib -- 192 ± 7.0a 59a
L. pneumophilac 10.5 ± 1.1 60 ± 9 --
M. tuberculosisd 10 ± 1 650 ± 70 0.193

PRPP = phosphoribosyl pyrophosphate.

aobtained with hypoxanthine as the purine base.

dPatta et al. (2015).

± standard error.