Table 4.
Univariable and Multivariable Cox regression for the outcome of posttransplant mortality in men
Variable | Unadjusted HR (95% CI) P-value |
Adjusted* HR (95% CI) P-value |
---|---|---|
Sarcopenic (SMI <48) | 3.65 (1.29–10.28) 0.01 |
4.39 (1.49–12.97) 0.007 |
MELD | 1.06 (1.01–1.11) 0.03 |
1.08 (1.02–1.13) 0.005 |
Age | 1.03 (0.98–1.08) 0.29 |
|
BMI | 0.94 (0.87–1.03) 0.17 |
|
HCC | 2.02 (0.66–6.12) 0.21 |
|
Diabetes | 2.01 (0.94–4.47) 0.09 |
|
Etiology of Liver Disease | ||
HCV | Reference | |
Alcohol | 0.29 (0.06–1.36) 0.12 |
|
NASH/NAFLD | 0.99 (0.12–7.90) 0.99 |
|
AIH/PSC/PBC | 1.07 (0.23–5.04) 0.94 |
|
HBV | 0.67 (0.14–3.16) 0.61 |
|
Other | 0.89 (0.24–3.37) 0.87 |
|
Hepatic Encephalopathy | ||
Absent | Reference | |
Altered Mood/Confusion | 1.89 (0.51–7.07) 0.34 |
|
Markedly Confused/Comatose | 2.69 (0.72–10.05) 0.14 |
|
Ascites | ||
Absent | Reference | |
Mild/Moderate | 1.09 (0.32–3.62) 0.89 |
|
Severe | 0.55 (0.12–2.45) 0.43 |
|
Donor age | 0.98 (0.94–1.02) 0.38 |
All variables associated with a P-value <0.2 in univariable analysis were evaluated for inclusion in the final multivariable model. The final multivariable model was developed using backwards elimination and included only those variables that were associated with a P <0.05.