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. Author manuscript; available in PMC: 2020 Jan 15.
Published in final edited form as: Neurobiol Aging. 2019 Mar 12;84:243.e1–243.e9. doi: 10.1016/j.neurobiolaging.2019.02.022

Fig. 2.

Fig. 2.

Manhattan plots of gene-based genome-wide association analyses in ADGC combined phase 1 and phase 2 samples of (A) the younger age (age 60–79 years, N = 11,358) and (B) the older age (age ≥ 80 years, N = 4,801). The red line denotes the gene-based genome-wide significance level of P value = 2.73×10−6 and blue line denotes the suggestive level of P value = 2.73×10−6. The gene symbols are shown here if their P values calculated by gene-based analyses are less than the suggestive level. APOE region is shown as representatives of significant genes on chromosome 19.