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. 2019 Oct 8;6:194. doi: 10.1038/s41597-019-0207-2

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© The Author(s) 2019

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Fig. 2 — QC metrics for MMDs. The first two PCs capturing the most variance are shown. PCA plots with red colored-border show PCs of merged data before batch-effect correction, which are colored by dataset (left). PCA plots with blue colored-border show PCs of merged data after Combat adjustment, which are colored by dataset (middle) and disease status (i.e., TT vs. NT; right). Ellipses are drawn one standard deviation away from the mean of the Gaussian fitted to each MMD.