Table 1.
Subject baseline characteristics.
| Characteristics | Levels of HDL cholesterol | |||||
|---|---|---|---|---|---|---|
| <40 mg/dl n = (6674) |
40–50 mg/dl n = (19999) |
50–60 mg/dl n = (29204) |
60–70 mg/dl n = (22975) |
70–80 mg/dl n = (12493) |
≥80 mg/dl n = (8725) |
|
| Age (years) | 51.31 ± 12.90 | 50.91 ± 13.08 | 51.23 ± 12.72 | 51.54 ± 12.50 | 53.31 ± 12.22 | 55.87 ± 11.52 |
| Male, n (%) | 5470(82.0) | 16817(84.1) | 23602(80.8) | 17848(77.7) | 9593(76.8) | 6583(75.4) |
| BMI (kg/m2) | 25.46 ± 3.60 | 25.50 ± 3.47 | 25.24 ± 3.43 | 24.84 ± 3.47 | 24.52 ± 3.47 | 24.30 ± 3.54 |
| Completed high school, n (%) | 1314(19.7) | 4616(23.1) | 6152(21.1) | 4291(18.7) | 1935(15.5) | 1116(12.8) |
| Daily smoker, n (%) | 2019(30.3) | 6784(33.9) | 8948(30.6) | 6323(27.5) | 3493(28.0) | 2475(28.4) |
| Daily alcohol user, n (%) | 860(12.9) | 3123(15.6) | 4929(16.9) | 4043(17.6) | 2532(20.3) | 1971(22.6) |
| Regular exercise, n (%) | 1276(19.1) | 3448(17.2) | 4409(15.1) | 2973(12.9) | 1735(13.9) | 1315(15.1) |
| Systolic BP, mmHg | 129.54 ± 20.23 | 129.89 ± 20.57 | 130.57 ± 20.97 | 130.90 ± 21.15 | 132.45 ± 21.49 | 135.10 ± 21.73 |
| Diastolic BP, mmHg | 82.76 ± 11.65 | 83.24 ± 11.75 | 83.43 ± 11.72 | 83.40 ± 11.77 | 83.81 ± 11.83 | 84.57 ± 12.00 |
| FBG, mmol/L | 5.43 ± 1.73 | 5.52 ± 1.62 | 5.50 ± 1.62 | 5.44 ± 1.64 | 5.43 ± 1.70 | 5.52 ± 2.01 |
| hs-CRP, mg/L |
0.89 (0.34,2.20) |
0.90 (0.36,2.30) |
0.85 (0.31,2.30) |
0.76 (0.30,2.10) |
0.72 (0.26,2.05) |
0.79 (0.27,2.47) |
| TC, mg/dl | 170.82 ± 40.03 | 181.53 ± 38.46 | 188.72 ± 42.67 | 192.95 ± 43.96 | 201.21 ± 44.34 | 216.05 ± 48.70 |
| LDL-C, mg/dl | 84.19 ± 34.18 | 93.25 ± 34.81 | 93.20 ± 35.11 | 90.29 ± 34.29 | 87.94 ± 34.52 | 85.83 ± 39.02 |
| Non-HDL-C, mg/dl | 136.33 ± 40.42 | 135.79 ± 38.32 | 133.65 ± 42.67 | 128.21 ± 43.94 | 126.82 ± 44.18 | 123.56 ± 49.97 |
| TG, mg/dl |
118.58 (77.88,191.15) |
120.35 (83.19,179.65) |
114.16 (80.53,171.68) |
108.85 (77.88,161.06) |
107.08 (76.99,161.95) |
109.73 (76.11,167.26) |
| eGFR, mL/min/1.73 m2 | 84.23 ± 29.52 | 84.20 ± 24.58 | 82.27 ± 25.34 | 80.32 ± 24.01 | 80.50 ± 25.15 | 80.79 ± 29.42 |
| Hypertension, n (%) | 2658(39.8) | 8352(41.8) | 12594(43.1) | 10103(44.0) | 5736(45.9) | 4428(50.8) |
| Diabetes mellitus, n (%) | 632(9.5) | 1904(9.5) | 2622(9.0) | 1928(8.4) | 1115(8.9) | 906(10.4) |
| History of stroke, n (%) | 207(3.1) | 585(2.9) | 781(2.7) | 495(2.2) | 280(2.2) | 190(2.2) |
| History of MI, n (%) | 102(1.5) | 274(1.4) | 395(1.4) | 278(1.2) | 141(1.1) | 114(1.3) |
| History of malignancy, n (%) | 26(0.4) | 69(0.3) | 99(0.3) | 89(0.4) | 48(0.4) | 45(0.5) |
| Antihypertensive drugs, n (%) | 860(12.9) | 2537(12.7) | 3397(11.6) | 2210(9.6) | 1253(10.0) | 964(11.0) |
| Lipid-lowering medication, n (%) | 70(1.0) | 220(1.1) | 267(0.9) | 190(0.8) | 121(1.0) | 90(1.0) |
| Mortality, n (%) | 499(7.5) | 1416(7.1) | 2084(7.1) | 1570(6.8) | 965(7.7) | 828(9.5) |
Abbreviations: BMI, body mass index; FBG, fasting blood glucose; hs-CRP, high sensitivity C-reactive protein; TC, total cholesterol; LDL-C, low-density lipoprotein cholesterol; TC, total cholesterol; TG, triglycerides; MI, myocardial infarction.