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. 2019 Oct 8;9:14463. doi: 10.1038/s41598-019-51058-3

Figure 7.

Figure 7

A fat-based diet, but not a carb- or protein-based diet enables E. coli to inhibit P. aeruginosa colonization and lethality in mice. (a) PA14 CFUs in faeces of immunocompromised mice fed on a fat- (a), protein- (b) or carbohydrate-based diet following inoculation with PA14 or co-inoculation with PA14 and E. coli BW25113 [n = 10]. **p < 0.005. Error bars represent standard deviation of the mean. (d) Survival of immunocompromised mice kept on a fat-, protein-, or carb-based diet and infected with PA14 or PA14 plus E. coli BW25113 [n = 10]. p = 0.04 for Fat PA14 + E. coli vs. Protein PA14 + E. coli and p = 0.0001 for Fat PA14 + E. coli vs. Carbs PA14 + E. coli.