Figure 1.

Induction of nuclear translocation of p65 in fibroblastic cells by MWCNTs in the lung. (A) Nuclear p65 in fibroblasts examined by double immunofluorescence staining of p65 (red) and Hsp47 (green), with DAPI nuclear staining (blue). The full images with scale bar are shown in Figure S1 . (B) Nuclear p65 in myofibroblasts examined by double immunofluorescence staining of p65 (red) and α-SMA (green), with DAPI nuclear staining (blue). The full images with scale bar are shown in Figure S2 . In (A) and (B), pink color generated from the overlap of red and blue indicates nuclear p65. (C) Number of nuclear p65+ Hsp47+ cells per unit area (2x10⁴ µm²) is presented as mean ± SD (n = 4). (D) Number of nuclear p65+ α-SMA+ cells per unit area (2x10⁴ µm²) is presented as mean ± SD (n = 4).