Table 5.
Summary of the 15 DNA regions differentially methylated between pronase isolated airway epithelial cells isolated from donors with and without asthma.
| Chromosome Location | Start Location | End Location | Region Width | Number of CpGs | Minimum FDR | Max. difference in β value | Mean difference in β value | Overlapping Promoters |
|---|---|---|---|---|---|---|---|---|
| chr20 | 32856747 | 32856898 | 152 | 2 | 0.0024633 | 0.08 | 0.08 | NA |
| chr10 | 44197967 | 44198369 | 403 | 3 | 0.0002902 | −0.14 | −0.12 | NA |
| chr10 | 133995286 | 133995387 | 102 | 3 | 0.0024633 | 0.11 | 0.08 | NA |
| chr2 | 133402827 | 133403009 | 183 | 3 | 0.0002206 | −0.09 | −0.08 | NA |
| chr3 | 195578240 | 195578280 | 41 | 3 | 0.0047179 | 0.15 | 0.12 | NA |
| chr6 | 152125861 | 152126092 | 232 | 3 | 0.0015607 | 0.15 | 0.10 | ESR1 |
| chr6 | 31238388 | 31239767 | 1380 | 15 | 2.818E-09 | −0.16 | −0.04 | HLA-C |
| chr2 | 3642098 | 3642967 | 870 | 11 | 4.476E-05 | 0.11 | 0.06 | COLEC11 |
| chr7 | 117067136 | 117067978 | 843 | 11 | 8.756E-05 | −0.12 | −0.05 | ASZ1 |
| chr6 | 291687 | 293285 | 1599 | 10 | 1.869E-21 | 0.24 | 0.19 | DUSP22 |
| chr15 | 91473059 | 91473569 | 511 | 8 | 0.0006853 | −0.08 | −0.04 | UNC45A |
| chr3 | 42977777 | 42978180 | 404 | 7 | 0.0001463 | −0.10 | −0.07 | KRBOX 1 |
| chr14 | 37135384 | 37136283 | 900 | 6 | 3.509E-05 | 0.10 | 0.08 | PAX9 |
| chr2 | 66659348 | 66659590 | 243 | 4 | 0.0010565 | −0.17 | −0.10 | MEIS1 |
| chr7 | 128696069 | 128696229 | 161 | 4 | 0.0006638 | −0.10 | −0.05 | TNPO3 |