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. 2019 Oct 8;10:4586. doi: 10.1038/s41467-019-12506-w

Fig. 2.

Fig. 2

Orthogonal photoactivation of multiple therapeutics. a Schematic showing the difference in emission profile between Control-SBs@azo-Psi and OP-SBs@azo-Psi with programmed activation using 980/808 nm laser. b Release of singlet oxygen from OP-SBs@azo-Psi in solution over time with 980 nm irradiation. c Step-wise release of singlet oxygen from OP-SBs@azo-Psi in solution with 980 nm irradiation. d Release of siRNA from OP-SBs@azo-Psi in solution over time with 808 nm irradiation. e Step-wise release of siRNA from OP-SBs@azo-Psi in solution with 808 nm irradiation. f Singlet oxygen production using 980 nm excitation of the same OP-SBs@azo-Psi at different time points. g Orthogonal activation of singlet oxygen production and siRNA release from OP-SBs@azo-Psi over time. h Non-orthogonal activation of singlet oxygen production and siRNA release from Control-SBs@azo-Psi over time. i Programmed activation of OP-SBs@azo-Psi with different durations of 980 and 808 nm NIR irradiation. Error bars represent the standard deviation of measurements from three (n = 3) distinct samples