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. 2019 Sep;11(Suppl 14):S1789–S1799. doi: 10.21037/jtd.2019.08.54

Table 2. Classification of drugs and toxins associated with PAH (adapted from the 6th WSPH).

Definite Possible
Aminorex Cocaine
Fenfluramine Phenylpropanolamine
Dexfenfluramine L-tryptophan
Benfluorex St John’s wort
Methamphetamines Amphetamines
Dasatinib Interferon-α and -β
Toxic rapeseed oil Alkylating agents
Bosutinib
Direct-acting antiviral agents against hepatitis C virus leflunomide
Indirubin (Chinese herb Qing-Dai)

PAH, pulmonary arterial hypertension.