Table 1.
Antibiotics recently approved by the Food and Drug Administration (FDA) and/or European Medicines Agency (EMA).
| Active Pharmaceutical Ingredient | Trade Name | Class/Comments |
|---|---|---|
| Doripenem | Doribax ™ (US) Finibax ™ (EU) |
Carbapenem |
| Ceftaroline fosamil | Teflaro ™ (US) Zinforo™ (EU) |
Cephalosporin |
| Ceftobiprole medocaril | Zevtera™(US) Mabelio™ (EU) |
Cephalosporin |
| Ceftolozane/tazobactam | Zerbaxa ™ (US/EU) | Combination antibiotic: cephalosporin/β-lactamase inhibitor |
| Ceftazidime/avibactam | Avycaz™ (US/EU) | Combination antibiotic: cephalosporin/β-lactamase inhibitor |
| Meropenem/vaborbactam | Vabomere™ (US) Carbavance™ (EU) |
Combination antibiotic: carbapenem/β-lactamase inhibitor |
| Imipenem/cilastatin/relebactam | Recarbrio ™ (US/EU) | Combination antibiotic: carbapenem/renal dehydropeptidase inhibitor/β-lactamase inhibitor |
| Telavancin | Vibativ™ (US) | Derivatives of either vancomycin or lipoglycopeptide |
| Dalbavancin | Dalvance™ (US) Xydalba™ (EU) |
Derivatives of either vancomycin or lipoglycopeptide |
| Oritavancin | Orbactiv™ (US/EU) | Derivatives of either vancomycin or lipoglycopeptide |
| Eravacycline | Xerava™ (US/EU) | Tetracycline derivatives |
| Sarecycline | Seysara™ (US) | Tetracycline derivatives |
| Omadacycline | Nuzyra™ (US) | Tetracycline derivatives |
| Bedaquiline, | Sirturo™ (US/EU) | Diarylquinoline (DARQ) |
| Tedizolid | Sivextro ™ (US/EU) | Oxazolidinone |
| Delafloxacin meglumine | Baxdela™ (US) | Fluoroquinolone |
| Plazomicin | Zemdri ™ (US) | Next-generation aminoglycoside (neoglycoside) |
| Lefamulin | Xenleta™ (US) | Pleuromutilin |
US: Trade name in the United States; EU: trade name in the member states of the European Union.