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. 2019 Sep 1;11(9):511. doi: 10.3390/toxins11090511

Table 2.

Diameters of the inhibition zone of all the active tested compounds against the reference Gram(+) and Gram(-) bacterial strains.

Inhibition Zone Assay Diameter of Inhibition Zone (mm) 1
Compound Gram-Positive
Staphylococcus aureus
ATCC 25923
Gram-Negative
Escherichia coli
ATCC 25922
Dihydroberberine·HCl (1) 7.800 n.a.
(S)-Glaucine (7) 7.600 n.a.
Canthin-6-one (28) 6.100 n.a.
Harmane (30) 4.360 8.640
Harmine (32) n.a. 6.250
Mytragine (34) 5.420 n.a.
Nigritanine (35) 10.39 n.a.
Paynantheine (36) 8.440 n.a.
Speciociliatine (38) 8.240 n.a.

1 Data represent the mean of three independent experiments with standard deviation (SD) not exceeding 0.2; n.a.: not active.