Table 1.
1H NMR (600 MHz) data for synthetic 12β-deoxyGTX2 (5) and 12β-deoxyGTX3 (3), and LWTX-1 (2) [19].
| 12β-deoxyGTX2 (5) | 12β-deoxyGTX3 (3) | LWTX-1 (2) | ||||
|---|---|---|---|---|---|---|
| No. | δH | Multiplicity (J in Hz) | δH | Multiplicity (J in Hz) | δH | (J in Hz) *** |
| 5 | 4.74 | s | 4.77 | s | 4.74 | s |
| 6 | 3.90 | t 4.3 | 3.90 | t 4.3 | 3.93 | 4.8 |
| 10α | 4.17 | d 12.3 | 4.15 | dd 11.5, 11.9 | 4.16 | 8.1, 11.6 |
| 10β | 3.96 | dd 11.5, 4.4 | 3.72 | dd 11.5, 4.3 | 3.67 | 5.4, 11.6 |
| 11 | 5.07 | t 3.1 | 4.91 * | n.d. ** | 4.90 | 5.4, 7.2, 8.1 |
| 12 | 4.45 | d 4.0 | 4.52 | d 7.0 | 4.49 | 7.2 |
| 13a | 3.96 | m | 4.27 | dd 13.9, 5.6 | 4.29 | 4.8 |
| 13b | 4.29 | dd 11.5, 4.4 | 4.33 | dd 13.9, 4.4 | 4.29 | 4.8 |
CD3COOD-D2O (4:96, v/v). The signal of CHD2COOD (2.06 ppm) was used as an internal reference. * estimated by TOCSY correlation, ** not determined, *** multiplicity is not shown in the reported data [19].