Table 3.
Small RNA profile of MSVs in mosquitoes (in vitro and in vivo).
| MSV | Family | Genome | Small RNAs | In Vivo /In Vitro |
Species | Reference |
|---|---|---|---|---|---|---|
| Cell fusion agent virus (CFAV) | Flaviviridae | +ssRNA | piRNAs and siRNAs | in vitro | Aag2 (Aedes aegypti) C6/36 (Aedes albopictus) |
[139,140] |
| Small RNA ** | in vitro | Aag2 | [141] | |||
| Calbertado virus | Flaviviridae | +ssRNA | siRNAs | in vitro | CT (Culex tarsalis) | [142] |
| Palm Creek virus (PCV) | Flaviviridae | +ssRNA | siRNAs and piRNA-like | in vivo | Aedes aegypti | [138] |
| Culex Y virus (CYV) | Birnaviridae | dsRNA | piRNA-like | in vitro | Aag2 C7/10 (Ae albopictus) U4.4 (Ae albopictus) |
[141] |
| siRNAs | in vitro | CT Aag2 U4.4 | [141,142,143] | |||
| Phasi-Charoen-like virus (PCLV) | Phenuiviridae | -ssRNA | Small RNAs ** | in vitro | Aag2 Ae (Ae aegypti) C7/10 |
[141] |
| siRNAs and piRNAs | in vitro | Aag2 CT |
[142,144] | |||
| siRNAs and piRNAs | in vivo | Ae aegypti | [145] | |||
| Aedes pseudoscutellaris reovirus | Reoviridae | dsRNA | Small RNAs ** | in vitro | Ae | [141] |
| Flock House virus | Nodaviridae | +ssRNA | siRNA | in vitro | CT | [142] |
| Culex narnavirus 1 | Narna-like *** | +ssRNA *** | siRNA | in vitro | CT | [142] |
| Aedes Anphevirus (AeAV) | n/a * | -ssRNA | piRNA and siRNA | in vitro | Aag2.wMelPop-CLA (Wolbachia strain wMelPop-CLA infected Aag2) |
[46] |
| Aedes albopictus densovirus 2 (Dipteran brevidensovirus 2) | Parvoviridae | ssDNA | Small RNAs ** | in vitro | Aag2 | [141] |
| Aedes densovirus (Dipteran brevidensovirus 1) | Parvoviridae | ssDNA | siRNA | in vitro | Aag2 | [142] |
* Family as of yet unassigned. Order: Mononegavirales; ** Small RNAs have been isolated and mapped against the virus. The type of small RNA has not been identified; *** Based on classification of Reference [142].