AML	adult acute myeloid leukemia
APC	antigen presenting cell
ART-Ig	asymmetric re-engineering technology—immunoglobulin
ATTACK	asymmetric tandem trimerbody for T cell activation and cancer killing
B-ALL	B cell acute lymphoblastic leukemia
BBB	blood-brain barrier
BEAT	bispecific engagement by antibodies based on the T cell receptor
BiKE	bispecific killer engager
BiTE	bispecific T-cell engager
CAR	chimeric antigen receptor
CD	cluster of differentiation
CIKs	cytokine-induced killers
CLL	chronic lymphocytic leukemia
CNS	central nervous system
CR	complete response
CRS	cytokine released syndrome
CTL	cytotoxic T lymphocytes
DART	dual affinity retargeting (antibody)
DLBCL	diffuse large B cell lymphoma
DVD-Ig	dual variable domain immunoglobulins
EGFRt	truncated version of epidermal growth factor receptor
EMA	European Medicines Agency
EpCAM	epithelial cell adhesion molecule
Fc	fragment, crystallizable
FIT-Ig	Fabs-in-tandem immunoglobulins
GVH, GVHD	graft-versus-host (disease)
HC	heavy chain
HLA	human leukocyte antigen
HSV-TK	herpes simplex virus thymidine kinase
iCasp9	inducible caspase-9
Ig	immunoglobulin
ImmTAC	immune-mobilizing monoclonal TCR against cancer
iNKT	invariant NKT (cells)
ITAM	immunoreceptor tyrosine activation motif
KIH	knobs-into-holes
LC	light chain
MATH	mutant-allele tumor heterogeneity
MHC	major histocompatibility complex
MM	multiple myeloma
NK	natural killer (cell)
NKG2D	natural killer group 2D
NKT	natural killer T (cell)
NSCLC	non-small cell lung cancer
OR	objective response
PBMCs	peripheral blood mononuclear cells
pMHC	peptide-MHC complex
PR	partial response
R/R	relapsed/refractory
sCAR	switchable chimeric antigen receptor
scFv	single chain, fragment variable
SEED	strand exchange engineered domain
SMAC	supramolecular activation cluster
TandAb	tandem diabody
TBE	target cell-biologic-effector cell (complex)
TCB	T-cell bispecifics
TCR	T-cell receptor
TILs	tumor infiltrating lymphocytes
TME	tumor microenvironment
TRBA	T-cell redirecting bispecific antibody
TriKE	trispecific killer engager
TITAC	trispecific T cell activating construct
US-FDA	United States Food and Drug Administration