. 2019 Aug 24;8(3):127. doi: 10.3390/antibiotics8030127

Table 1.

Proposed novel metrics for adjustment of antimicrobial use by quality of care.

Adjusted AU	Formula
APBL	$\frac{A U_{A P B L}}{\begin{matrix} P r o p o r t i o n o f p a t i e n t s w i t h g r a m - n e g a t i v e B S I o r s e p s i s \\ r e c e i v i n g a p p r o p r i a t e e m p i r i c a l a n t i m i c r o b i a l t h e r a p y \end{matrix}}$
Carbapenems	$\frac{A U_{C a r b a p e n e m s}}{\begin{matrix} P r o p o r t i o n o f p a t i e n t s w i t h g r a m - n e g a t i v e B S I o r s e p s i s \\ r e c e i v i n g a p p r o p r i a t e e m p i r i c a l a n t i m i c r o b i a l t h e r a p y \end{matrix}}$
Anti-MRSA agents	$\frac{A U_{A n t i - M R S A a g e n t s}}{\begin{matrix} P r o p o r t i o n o f p a t i e n t s w i t h g r a m - p o s i t i v e B S I o r s e p s i s \\ r e c e i v i n g a p p r o p r i a t e e m p i r i c a l a n t i m i c r o b i a l t h e r a p y \end{matrix}}$
Anti-VRE agents	$\frac{A U_{A n t i - V R E a g e n t s}}{\begin{matrix} P r o p o r t i o n o f p a t i e n t s w i t h g r a m - p o s i t i v e B S I o r s e p s i s \\ r e c e i v i n g a p p r o p r i a t e e m p i r i c a l a n t i m i c r o b i a l t h e r a p y \end{matrix}}$

Note: AU: antimicrobial use; APBL: antipseudomonal beta-lactams; MRSA: methicillin-resistant Staphylococcus aureus; VRE: vancomycin-resistant Enterococcus species; BSI: bloodstream infections.