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. 2019 Oct 9;21(10):1284–1296. doi: 10.1093/neuonc/noz128

Fig. 2.

Fig. 2

CircFOXO3 KD suppressed GBM cell proliferation, colony formation, invasion, and migration. (A, B) CCK-8 assays were performed using U87-MG and U251-MG with or without circFOXO3-KD. (C–F) Colony formation assays were performed using U87-MG and U251-MG with or without circFOXO3 KD (magnification: 100×; scale bar = 200 μm). Colony number (E) and size (F) were calculated. (G–I) Transwell analyses of U87-MG and U251-MG with or without circFOXO3 KD were performed. Representative staining images are presented (magnification: 200×; scale bar = 100 μm). (J–L) Wound healing assays were conducted on U87-MG and U251-MG with or without circFOXO3 KD (magnification: 100×; scale bar = 200 μm). A multiple comparisons test adjusted P-value of <0.05 was considered statistically significant. Error bars represent the mean ± SD.