Table 4.
Amino acid changes in the Italian isolates and analysis of the selective pressure.
| NO OF VARIANTS (/76) | % | AA CHANGES | POSITION | GENE | METHOD |
|---|---|---|---|---|---|
| 75 | 0.99 | V -> A | 416 (139) | prM | - |
| 17 | 0.23 | T -> A | 427 (143) | prM | - |
| 3 | 0.04 | I -> S | 473 (158) | prM | - |
| 15 | 0.2 | A -> T | 1021 (341) | ENV | - |
| 17 | 0.23 | H -> Y | 2476 (826) | NS1 | - |
| 5 | 0.07 | I -> V | 2509 (837) | NS1 | - |
| 4 | 0.05 | I -> F | 2740 (914) | NS1 | - |
| 17 | 0.23 | A -> V | 2810 (937) | NS1 | - |
| 75 | 0.99 | V -> A | 2933 (978) | NS1 | - |
| 75 | 0.99 | S -> C | 4003 (1335) | NS2A | - |
| 3 | 0.04 | R -> G | 5263 (1755) | NS3 | - |
| 14 | 0.18 | I -> V | 5863 (1955) | NS3 | - |
| 75 | 0.99 | T -> I | 6629 (2210) | NS4A | - |
| 6 | 0.08 | H -> R | 7712 (2571) | NS5 | IFEL |
| 17 | 0.23 | Y -> H | 8191 (2731) | NS5 | IFEL |
| 75 | 0.99 | S -> G | 8266 (2756) | NS5 | - |
| 18 | 0.24 | N -> S | 8603 (2868) | NS5 | IFEL |
| 75 | 0.99 | H -> R | 8924 (2975) | NS5 | - |
| 75 | 0.99 | A -> T | 9535 (3179) | NS5 | - |
| 18 | 0.24 | V -> A | 10241 (3414) | NS5 | - |