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. 2019 Oct 8;18:131. doi: 10.1186/s12933-019-0930-1

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Triangular relationship among GRS, T2D and multi-vessel disease. OR_G represented the association between GRS and T2D risk after adjustment for age, sex, and BMI; OR_D represented the association between T2D and multi-vessel disease; OR_O represented the observed association of GRS with multi-vessel disease; and OR_E represented the expected association of GRS with multi-vessel disease. OR_D, OR_O, and OR_E were calculated after adjustment for age, sex, BMI, smoking status, hypertension, and hypercholesterolemia