Table 1.
Baseline characteristics among 1414 patients with ACS
| Variables | Total | Single-vessel disease | Multi-vessel disease | P value |
|---|---|---|---|---|
| No. of patients | n = 1414 | n = 490 | n = 924 | |
| Demographics | ||||
| Age, median (IQR), years | 60 (53–68) | 58 (49–65) | 61 (55–69) | < 0.001 |
| BMI, median (IQR), kg/m2 | 24.7 (22.7–26.9) | 24.7 (22.5–26.8) | 24.7 (22.9–27.0) | 0.325 |
| Male, n (%) | 1112 (78.6) | 380 (77.5) | 732 (79.2) | 0.509 |
| Current smoking, n (%) | 588 (41.6) | 201 (41.0) | 387 (41.9) | 0.798 |
| Diagnosis, n (%) | ||||
| NSTEMI | 271 (19.2) | 89 (18.2) | 182 (19.7) | |
| STEMI | 340 (24.0) | 113 (23.1) | 227 (24.6) | 0.544 |
| UA | 803 (56.8) | 288 (58.8) | 515 (55.7) | |
| Medical history, n (%) | ||||
| Hypertension | 753 (53.3) | 219 (44.7) | 534 (57.8) | < 0.001 |
| Type 2 diabetes | 288 (20.4) | 69 (14.1) | 219 (23.7) | < 0.001 |
| Hypercholesterolemia | 255 (18.0) | 81 (16.5) | 174 (18.8) | 0.318 |
| Prior myocardial infarction | 121 (8.6) | 34 (7.0) | 87 (9.4) | 0.138 |
| Prior revascularization | 112 (7.9) | 32 (6.5) | 80 (8.6) | 0.192 |
| Stroke/transient ischemic arrack (TIA) | 71 (5.0) | 19 (3.9) | 52 (5.6) | 0.192 |
| Heart failure | 12 (0.8) | 2 (0.4) | 10 (1.1) | 0.236 |
| Chronic angina | 168 (11.9) | 43 (8.8) | 125 (13.5) | 0.011 |
| Chronic renal failure | 8 (0.6) | 3 (0.6) | 5 (0.5) | 1.000 |
| Chronic obstructive pulmonary diseases (COPD)/other chronic lung diseases (CLD) | 8 (0.6) | 4 (0.8) | 4 (0.4) | 0.459 |
| Peripheral vascular disease | 11 (0.8) | 2 (0.4) | 9 (1.0) | 0.348 |
| Genetic information | ||||
| Family history of CAD, n (%) | 117 (8.3) | 36 (7.3) | 81 (8.8) | 0.412 |
| T2D-GRS, median (IQR) | 48.5 (46.0–51.1) | 48.1 (45.5–50.5) | 48.7 (46.3–51.3) | < 0.001 |