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. 2019 Oct 9;17:77. doi: 10.1186/s12915-019-0698-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Temperature-dependent Phosphorylation. a High-temperature phosphorylation sites of DBM RyR Repeat34 measured by LC-MS/MS. The buried sites are colored in pink, the sites located in the phosphorylation loop are colored in blue, and the other sites are colored in green. RyR2 HD1 domain is shown in yellow. b Low-temperature phosphorylation sites of DBM RyR Repeat34 measured by LC-MS/MS. The color scheme is the same as in panel A. c Phosphorylation sites of full-length RyR from silkworm measured by LC-MS/MS. The color scheme is the same as panel A. d High-temperature phosphorylation sites of mouse RyR2 Repeat34 measured by LC-MS/MS