Table 1.

A comparison of different biosensor techniques for tau detection.

Techniques	Modified	Linear Rang	LOD	Target	Ref.
Fluorescence	FAM/ssDNA	-	28 nM	Tau441	[10]
SPR	aptamer/tau/anti-tau/ MUA	10–100 fM	10 fM	Tau381	[17]
	tau/mAb/protein G	0.01–100 ng/mL	10 pg/mL	Tau441	[18]
	tau/anti-tau/11-MUA	10–2000 pg/mL	2.4 pg/mL	T-tau	[19]
Electrochemistry	tau/anti-tau/pPG/GO	0.5–15.1 nM	0.15 nM	T-tau	[13]
	tau/anti-tau/protein G/ DTSSP	10−14–10−7 M	0.03 pM	Tau441	[14]
	CS-Au-Aptamer/tau/anti-tau/MPA	0.5–100.0 pM	0.42 pM	Tau381	[20]
	tau/tau	0.2–1.0 μM	-	Tau441	[15]
	tau/anti-tau/MPA- SAM	103–105 pg/mL	-	T-tau	[16]

FAM: 5-Carboxyfluorescein; MUA: 11-mercaptoundecanoic acid; pPG: poly (propyleneglycol); GO: graphene oxide; DTSSP: 3, 3’-dithiobis (sulfosuccinimidyl propionate); CS: cysteamine; MPA-SAM: Self-assembled monolayers of 3-mercaptopropionic acid.