Table 1.
Characteristics of participants with sickle cell disease and controls
| Parameter | All (n=461) | Males (n=299) | Females (n=232) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SCD (n=245) | Control (n=216) | Statistics | SCD (n=122) | Control (n=107) | Statistics | SCD (n=123) | Controls (n=109) | Statistics | |
| Age in years median (IQR) | 25.0 (21.0-31.0) |
24.0 (22.0-27.0) |
Z=−0.45, P=0.65 |
25.0 (20.0-30.0) |
25.0 (23.0-28.0) |
Z=0.50, P=0.63 |
25.0 (21.0-32.0) |
23.0 (22.0-26.0) |
Z=−1.17, P=0.24 |
| Age group (years) (%) | |||||||||
| 14-24 | 118 (48.2) | 122 (56.5) |
χ2=4.41, P=0.22 |
60 (49.2) | 51 (47.7) |
χ2=1.08, P=0.78 |
58 (47.2) | 71 (65.1) |
χ2=7.74, P=0.05 |
| 25-34 | 92 (37.6) | 74 (34.3) | 50 (41.0) | 49 (45.8) | 42 (34.1) | 25 (22.9) | |||
| 35-44 | 26 (10.6) | 14 (6.5) | 7 (5.7) | 4 (3.7) | 19 (15.4) | 10 (9.2) | |||
| ≥45 | 9 (3.7) | 6 (2.8) | 5 (4.1) | 3 (2.8) | 4 (3.3) | 3 (2.8) | |||
| Height in meters median (IQR) | 1.67 (1.60-1.73) | 1.67 (1.61-1.75) |
Z=1.3, P=0.19 |
1.72 (1.65-1.77) | 1.74 (1.68-1.79) |
Z=−2.0, P=0.05 |
1.62 (1.58-1.67) | 1.62 (1.59-1.69) |
Z=−0.68, P=0.68 |
| BMI in Kg/m2 median (IQR) | 20.1 (18.2-21.8) | 22.6 (21.1-25.3) |
Z=−10.10, P=<0.001 |
19.2 (17.7-21.3) | 22.5 (21.2-24.9) |
Z=−8.40, P=<0.001 |
20.5 (18.8-22.4) | 22.7 (20.9-25.8) |
Z=−5.95, P=<0.001 |
| SPO2 in % median (IQR) | 96.0 (94.0-98.0) | 98.0 (98.0-98.0) |
Z=−13.50, P=<0.001 |
95.0 (93.0-97.0) | 98.0 (98.0-98.0) |
Z=−10.40, P<0.001 |
96.0 (94.0-98.0) | 98.0 (98.0-98.0) |
Z=−8.61, P<0.001 |
IQR=Interquartile range, BMI=Body mass index, SPO2=Oxygen saturation, SCD=Sickle cell disease