Table 4.
Sensitivity, specificity, positive and negative predictive values, and positive and negative likelihood ratios for the diagnosis of infectious pleural effusion using the two models
| Likelihood (%) | Sensitivity (CI) (%) | Specificity (CI) (%) | PPV (CI) (%) | |||
|---|---|---|---|---|---|---|
| Model 1 | Model 2 | Model 1 | Model 2 | Model 1 | Model 2 | |
| 10 | 90.1 (84.2-94.3) | 92.1 ((86.6-95.8) | 61.5 (56-66) | 62.2 (57.4-66.8) | 45 (40-60) | 46.1 (41.2-62.8) |
| 20 | 82.9 (75.9-88.5) | 86.2 (79.6-91.2) | 76.5 (72.2-80.4) | 77.4 (73.2-81.2) | 55.3 (49.7-66.2) | 57.2 (51.6-69.1) |
| 30 | 77 (69.5-83.4) | 78.3 (70.9-84.6) | 86.4 (82.8-89.5) | 86.9 (83.3-89.9) | 66.5 (60-74.9) | 67.6 (61.2-76) |
| 40 | 69.1 (61.1-76.3) | 72.3 (64.6-79.3) | 90.3 (87.1-92.9) | 91.2 (88.2-93.7) | 71.4 (64.4-78.3) | 74.3 (67.4-80.9) |
| 50 | 63.1 (55-70.8) | 68.4 (60.4-75.7) | 92.4 (89.5-94.7) | 94 (91.3-96) | 74.4 (67-80.4) | 80 (72.9-85.2) |
| 60 | 57.2 (49-65) | 58.5 (50.3-66.5) | 96 (94-97.8) | 96.8 (94.6-98.2) | 84.4 (76.8-88.4) | 86.4 (78.9-89.9) |
| 70 | 51.3 (43-59.4) | 51.3 (43-59.5) | 97.9 (96.1-99) | 97.9 (96.1-99) | 89.6 (81.9-92.3) | 89.6 (81.9-92.4) |
| 80 | 35.5 (27.9-43.7) | 34.8 (27.3-43) | 99.3 (97.9-99.8) | 99.1 (97.6-99.7) | 94.7 (85.9-96.2) | 93 (83.7-94.9) |
| 90 | 17.1 (11.5-24) | 17.7 (12-24.8) | 99.5 (98.3-99.9) | 99.8 (98.7-99.9) | 92.8 (78.1-95.2) | 96.4 (82.8-97.6) |
| Likelihood (%) | NPV (CI) (%) | LR+ (CI) | LR- (CI) | |||
| Model 1 | Model 2 | Model 1 | Model 2 | Model 1 | Model 2 | |
| 10 | 94.7 (91.2-95.6) | 95.7 (92.6-96.5) | 2.34 (2.05-2.66) | 2.43 (2.14-2.77) | 0.16 (0.1-0.26) | 0.12 (0.07-0.21) |
| 20 | 92.7 (89.2-94.1) | 94.1 (90.9-95.3) | 3.53 (2.93-4.24) | 3.81 (3.17-4.59) | 0.22 (0.16-0.32) | 0.17 (0.12-0.26) |
| 30 | 91.5 (87.9-93.4) | 91.9 (88.5-93.9) | 5.66 (4.39-7.28) | 5.96 (4.61-7.70) | 0.26 (0.20-0.36) | 0.25 (0.18-0.34) |
| 40 | 89.3 (85.4-92.2) | 90.4 (86.7-93.1) | 7.13 (5.25-9.69) | 8.26 (6-11.3) | 0.34 (0.27-0.43) | 0.30 (0.23-0.39) |
| 50 | 87.7 (83.6-91.3) | 89.5 (85.7-92.9) | 8.30 (5.85-11.78) | 11.4 (7.7-16.8) | 0.39 (0.32-0.49) | 0.33 (0.26-0.42) |
| 60 | 86.5 (82-92) | 86.9 (82.7-92.5) | 15.5 (9.4-25.6) | 18.2 (10.7-30.9) | 0.44 (0.37-0.53) | 0.42 (0.35-0.51) |
| 70 | 85.1 (80.4-92.6) | 85.2 (80.5-92.7) | 24.74 (12.72-48.1) | 24.7 (12.7-48.1) | 0.49 (0.42-0.58) | 0.49 (0.42-0.58) |
| 80 | 81.4 (75.6-95.5) | 81.3 (75.3-94.1) | 51.39 (16.3-161.96) | 37.8 (13.9-102.8) | 0.64 (0.57-0.73) | 0.65 (0.58-0.73) |
| 90 | 77.4 (68.3-96.6) | 77.6 (68.7-99.3) | 37.11 (8.91-154.53) | 77.1 (10.6-562.5) | 0.83 (0.77-0.89) | 0.82 (0.76-0.88) |
CI=Confidence intervals, LR+=Positive likelihood ratio, LR-=Negative likelihood ratio, NPV=Negative predictive value, PPV=Positive predictive value