Figure 2.
Sex comparison of the inducible reservoir as measured by the tat/rev induced limiting dilution assay (TILDA) in isolated resting CD4+ T cells. A, Comparison of TILDA values between men and women did not show a statistically significant difference. B, When normalized to integrated human immunodeficiency virus (HIV) DNA levels, female subjects had generally lower ratios of TILDA to integrated HIV DNA, although this did not achieve statistical significance. Median and interquartile range is shown for all values; statistical comparison maximum likelihood estimates for TILDA comparison and with a customized maximum likelihood model for the ratio. Abbreviations: iHIV, integrated human immunodeficiency virus; msHIV, multiply spliced human immunodeficiency virus; TILDA, tat/rev induced limiting dilution assay.