Table 1.
Cardiac and laboratory parameters before and following exchange transfusion in 32 SCD patients
| Parameter | Pretransfusion | Posttransfusion | Wilcoxon P |
|---|---|---|---|
| BSA, m2 | 1.8 ± 0.3 | 1.8 ± 0.3 | .09 |
| SBP, mm Hg | 120 ± 14 | 119 ± 13 | .67 |
| DBP, mm Hg | 65 ± 13 | 61 ± 9 | .25 |
| Heart rate, beats/min | 78 ± 12 | 74 ± 11 | .03 |
| TR, cm/s | 2.5 ± 0.4 | 2.6 ± 0.3 | .99 |
| RVSP, mm Hg | 31.0 ± 8.2 | 31.7 ± 6.7 | .90 |
| LVEDD, mm | 49.4 ± 5.2 | 50.2 ± 5.8 | .23 |
| LVESD, mm | 32.7 ± 4.8 | 32.3 ± 4.4 | .42 |
| LVEDV/BSA, mL/m2 | 69.4 ± 17.7 | 76.4 ± 18.9 | .002 |
| LV mass index, g/m2 | 91.2 ± 20.1 | 94.0 ± 21.9 | .40 |
| LA volume index, mL/m2 | 42.5 ± 15.5 | 42.4 ± 11.7 | .52 |
| EF, % | 62 ± 6.4 | 64 ± 4.9 | .14 |
| CO, L/min | 6.6 ± 2.0 | 6.2 ± 2.0 | .36 |
| E/A ratio | 1.8 ± 0.8 | 1.8 ± 0.6 | .97 |
| Sep E/e′, cm/s | 10.8 ± 2.3 | 10.9 ± 2.4 | .34 |
| Lat E/e′, cm/s | 17.3 ± 3.7 | 16.0 ± 3.9 | .04 |
| Hemoglobin, g/dL | 9.2 ± 1.5 | 9.9 ± 0.7 | .02 |
| Total bilirubin, mg/dL | 2.5 ± 2.1 | 1.4 ± 0.9 | <.0001 |
| Serum creatinine, mg/dL | 0.8 ± 0.5 | 0.7 ± 0.4 | .04 |
| Reticulocyte count, % | 9.3 ± 5.4 | 3.6 ± 2.5 | <.0001 |
| LDH, U/L | 353 ± 108 | 322 ± 112 | .09 |
CO, cardiac output; DBP, diastolic blood pressure; EF, ejection fraction; LDH, lactic acid dehydrogenase; LVEDD, left ventricular end-diastolic diameter; LVEDV, left ventricular end-diastolic volume; LVESD, left ventricular end-systolic diameter; RVSP, right ventricular systolic pressure; SBP, systolic blood pressure.