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Table 2.

Cardiac and laboratory parameters before and following HSCT in 44 patients with successful transplants

Parameter Baseline 3 mo 6 mo 1 y
BSA, m2 1.87 ± 0.21 1.87 ± 0.23 1.89 ± 0.22^ 1.92 ± 0.23***
SBP, mm Hg 120 ± 14 123 ± 12 122 ± 15 121 ± 16
DBP, mm Hg 64 ± 12 71 ± 10*** 72 ± 10*** 71 ± 12*
Heart rate, beats/min 75 ± 14 74 ± 13 78 ± 15 76 ± 15
TR, cm/s 2.6 ± 0.34 2.5 ± 0.20 2.5 ± 0.27 2.4 ± 0.29*
RVSP, mm Hg 33 ± 7.2 30 ± 4.4 31 ± 5.8 29 ± 5.5
LVEDD, mm 51 ± 4.9 49 ± 4.6* 48 ± 4.8*** 48 ± 4.9***
LVESD, mm 33 ± 4.2 34 ± 5.3 33 ± 6.5 33 ± 4.0
LVEDV/BSA, mL/m2 83 ± 22 69 ± 21*** 68 ± 20*** 65 ± 18***
LV mass index, g/m2 101 ± 27 90 ± 25 86 ± 25*** 89 ± 22**
LA volume index, mL/m2 46 ± 14 36 ± 18* 38 ± 15*** 36 ± 12***
EF, % 65 ± 4.9 57 ± 5.1*** 58 ± 6.1*** 60 ± 5.2***
CO, L/min 6.1 ± 1.9 5.1 ± 1.2 5.7 ± 1.6 5.6 ± 1.9
E/A ratio 1.7 ± 0.6 1.5 ± 0.5 1.4 ± 0.5* 1.5 ± 0.5
Sep E/e′, cm/s 10.8 ± 2.6 9.3 ± 2.3*** 8.7 ± 2.0*** 9.1 ± 2.0***
Lat E/e′, cm/s 16 ± 3.9 15 ± 4.6 14 ± 4.2 14 ± 3.2*
Hemoglobin, g/dL 9.5 ± 0.9 11.3 ± 2.0*** 11.7 ± 2.1*** 12.3 ± 1.9***
Total bilirubin, mg/dL 2.1 ± 3.1 0.4 ± 0.3*** 0.6 ± 0.3*** 0.5 ± 0.3***
Serum creatinine, mg/dL 1.0 ± 1.5 1.4 ± 2.3*** 1.5 ± 3.1*** 1.4 ± 2.8***
Reticulocyte count, % 3.5 ± 2.8 2.1 ± 1.5*** 2.2 ± 1.3 2.0 ± 1.2
LDH, U/L 338 ± 122 248 ± 80*** 253 ± 127*** 208 ± 61***,^^
6-min walk, m 509 ± 81 501 ± 98 525 ± 113 544 ± 83**
*

P ≤ .05, **P ≤ .01, ***P ≤ .005 for follow-up studies compared with baseline echo.

^

P ≤ .05 and ^^P ≤ .01 for 3- vs 6-month studies and 6 vs 12 months.