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. 2019 Aug 12;4:27. Originally published 2019 Feb 8. [Version 2] doi: 10.12688/wellcomeopenres.15003.2

Table 4b. Children without malaria: Odds of death at each level of haemoglobin (Hb) in those who received transfusion versus no transfusion.

Hb level
g/dl
N Died Not
transfusion
Deaths non-
transfused
Case
fatality
Transfused Deaths
transfused
Case
fatality
Odds ratio (95% CI) P value
<3 266 20 54 4 7.4% 212 16 7.55% 1.02 (0.33 - 3.19) 0.972
3-3.9 323 23 64 5 7.8% 259 18 6.95% 0.88 (0.31 - 2.47) 0.81
4-4.9 436 40 214 15 7.0% 222 25 11.26% 1.68 (0.86 - 3.29) 0.127
5-5.9 586 61 483 34 7.0% 103 27 26.21% 4.69 (2.68 - 8.22) <0.001
6-6.9 1013 121 931 85 9.1% 82 36 43.90% 7.79 (4.77 - 12.71) <0.001
7-7.9 1884 180 1,815 142 7.8% 69 38 55.07% 14.44 (8.72 - 23.91) <0.001
8-8.9 3154 209 3,090 173 5.6% 64 36 56.25% 21.68 (12.93 - 36.36) <0.001
9-9.9 4316 192 4,267 169 3.96% 49 23 46.94% 21.45 (11.99 - 38.38) <0.001
10-10.9 4115 142 4,074 129 3.2% 41 13 31.71% 14.20 (7.19 - 28.05) <0.001
>=11 4171 193 4,128 174 4.2% 43 19 44.19% 17.99 (9.67 - 33.47) <0.001
Total 20264 1181 19120 930 4.9% 1144 251 21.9%

Diagnoses for those with Hb 8.0g and above (tables 3a and b) who were transfused:

Congenital abnormality (5); cerebral palsy (3); gastroenteritis (18); hepatitis (3), HIV (22); hypersplenism (1); Lower respiratory tract infection (18); malaria (45); malignancies (15); malnutrition (56); poisoning (5); renal failure (7); sickle cell disease (14); sepsis (23); snake bite (1); surgical (7); trauma (5) and unknown (6).