Fig. 3.

Overview of MAR ASD findings. Numerous studies provide evidence of the role for maternal autoantibodies to proteins in the developing brain in ASD. Beginning with the first western blots of fetal brain proteins, studies have shown a relationship between the presence of the MAR ASD autoantibodies and behavioral deficits, the cMET allele polymorphism, metabolic conditions during pregnancy, enlarged brain volume in both humans and animal models, and changes in the way neurons develop following exposure