Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Neratinib pharmacokinetics. (A) Neratinib concentration versus time over 24 hours. The outlier at 200 mg/d (upper arrow) developed a dose-limiting toxicity; the outlier at 160 mg/d (lower arrow) was taking pantoprazole. (B) Neratinib trough concentration at 24 hours (C24) on day 1, cycle 2, after dosing, with indication of response. CR, complete response; PD, progressive disease; PR, partial response.
