Table 4. Detailed Comparison of 36-Month Outcome Data Across Familial Risk Groups in Children Without ASD.
| Variable | Mean (SD) | P Value | d | ||
|---|---|---|---|---|---|
| Single Incidence | Multiplex | Raw | FDR | ||
| Cognitive abilities (MSEL) | |||||
| Visual reception | 59.14 (12.26) | 54.70 (14.85) | .05 | .22 | 0.33 |
| Fine motor | 50.66 (13.03) | 46.96 (14.32) | .07 | .22 | 0.27 |
| Receptive language | 51.80 (9.91) | 47.61 (8.80) | .003 | .04 | 0.45 |
| Expressive language | 52.28 (9.38) | 50.39 (9.89) | .20 | .29 | 0.20 |
| Observed ASD symptoms (ADOS) | |||||
| Social affect | 2.38 (1.74) | 2.63 (1.68) | .35 | .41 | 0.15 |
| RRB | 3.68 (2.58) | 4.41 (2.48) | .06 | .22 | 0.29 |
| Reported ASD symptoms (ADI-R) | |||||
| Social interaction | 2.66 (2.30) | 3.82 (3.84) | .13 | .29 | 0.37 |
| Communication | 2.39 (2.50) | 3.29 (3.47) | .20 | .29 | 0.30 |
| RRB | 0.73 (1.39) | 1.29 (1.86) | .14 | .29 | 0.34 |
| Adaptive skills (Vineland-II) | |||||
| Communication | 99.57 (13.61) | 96.03 (14.33) | .17 | .29 | 0.25 |
| Daily living skills | 93.47 (13.43) | 90.24 (13.71) | .23 | .30 | 0.24 |
| Socialization | 96.17 (12.03) | 93.85 (17.62) | .46 | .50 | 0.15 |
| Motor skills | 93.90 (11.62) | 93.07 (16.81) | .80 | .80 | 0.06 |
Abbreviations: ADI-R, Autism Diagnostic Interview–Revised; ADOS, Autism Diagnostic Observation Schedule; ASD, autism spectrum disorder; FDR, false discovery rate; MSEL, Mullen Scales of Early Learning; RRB, restricted, repetitive behavior; Vineland-II, Vineland Adaptive Behavior Scales–Second Edition.