Table 4.

Similarities and differences between responses of rat sensory neurons to heat (H) and capsaicin (C)

Similarities	Differences
Co-segregation of C and H responses at whole-cell level	Weak correlation of amplitudes of C and H responses
Similar I–V curves (outward rectification) for whole-cell and single-channel currents
Nonselective increase in cation permeability	PCa/PNagreater for C than H responses
C and H both elicit Ca uptake	Maximal Ca uptake greater for C than for H
C and H both induce single-channel events in excised patches
Similar single-channel characteristics (amplitude, mean open time, substate level)	Segregation of sensitivity to C and H at single-channel level