Fig. 5.

Medial temporal lobe activations (amygdala and hippocampus) in two individual subjects. Each individual subplot shows the localization of the activation on the subject's individual T1-weighted MR scan together with a 3D plot of the activation pattern over time. All activation maps are thresholded at p< 0.05 for display purposes. This plot shows evoked hemodynamic responses to CS+_unpaired stimuli in relation to the stimulus [Peri-stimulus time (s) vs % Signal change]. The additional third dimension (scans) illustrates how this evoked response changes throughout the experiment. All four regions show significant decreases of evoked responses, indicated by smaller or negative amplitudes toward the end of the experiment.