Fig. 4.

DOR activation in the NAc rescues social avoidance in mice susceptible to CSDS. a A timeline of experiments. After the animals were categorized as either resilient or susceptible to CSDS by SI (pre), they received bilateral infusion of DOR agonist SNC80 (8 mg/kg) prior to a second SI (post). b SNC80 infusion significantly increased the interaction time in the susceptible mice but it did not affect resilients or non-stressed controls (*p < 0.05, post hoc; two-way repeated measures ANOVA: p < 0.0001 for treatment effect and p < 0.01 for interaction effect)