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. 2019 Feb 6;44(7):1239–1246. doi: 10.1038/s41386-019-0328-5

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Time–frequency analysis of the mean difference (placebo-ketamine) of the auditory evoked gamma-band response (aeGBR) power in the timeframe between 50 ms pre-stimulus and 200 ms post-stimulus. The aeGBR can be seen as an increased activity about 50 ms after stimulus presentation (dashed line) and around 40 Hz in the frequency range. Scalp topographies are displayed for each condition as well as a difference topography in the same scaling as the time–frequency analysis. The scalp topographies were calculated for the timeframe 50–75 ms and a frequency of 40 Hz. The aeGBR power (b) and phase-locking factor (PLF) (c) are displayed as the results of the wavelet analysis (complex Morlet wavelet) focused on the activity around 40 Hz for the ketamine condition (red line) and the placebo condition (black line) (**p < 0.01)