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. 2019 Apr 14;44(9):1518–1523. doi: 10.1038/s41386-019-0389-5
International standard for significance: p < 0.000000050 (i.e., p < 5 × 10−8)
2009 [25] p-value (N ~ 7000) p = 0.000000048
2011 [26] p-value (N ~ 52,000) p = 0.0000000000022
2014 [6] p-value (N ~ 150,000) p = 0.00000000000000000000000000000035