Table 1. Relationship between clinicopathologic characteristics of tumor and expression levels of miR-382 and miR-210 in gastric adenocarcinoma.
| Clinicopathological | microRNA-382 | p | microRNA-210 | p | |||
|---|---|---|---|---|---|---|---|
| Characteristics | All | Low expression | High expression | Low expression | High expression | ||
| n (%) | n (%) | n (%) | n (%) | n (%) | |||
| Age at diagnosis, years | 0.349 | 0.034 | |||||
| <63 | 90 (49.2) | 78 (47.9) | 12 (60.0) | 71 (54.2) | 19 (36.5) | ||
| ≥63 | 93 (50.8) | 85 (52.1) | 8 (40.0) | 60 (45.8) | 33 (63.5) | ||
| Sex | 0.788 | 0.854 | |||||
| Male | 135 (73.8) | 121 (74.2) | 14 (70.0) | 95 (73.1) | 40 (75.5) | ||
| Female | 48 (26.2) | 42 (25.8) | 6 (30.0) | 36 (26.9) | 13 (24.5) | ||
| Lauren classification | 0.663 | 0.937 | |||||
| Intestinal | 67 (36.6) | 61 (37.4) | 6 (30.0) | 48 (36.9) | 19 (35.8) | ||
| Diffuse | 101 (55.2) | 88 (54.0) | 13 (65.0) | 72 (55.4) | 29 (54.7) | ||
| Mixed | 15 (8.2) | 14 (8.6) | 1 (5.0) | 10 (7.7) | 5 (9.4) | ||
| EGCa vs AGCb | 0.008 | <0.001 | |||||
| EGC | 91 (49.7) | 87 (53.4) | 4 (20.0) | 81 (61.8) | 10 (19.2) | ||
| AGC | 92 (50.3) | 76 (46.6) | 16 (80.0) | 50 (38.2) | 42 (80.8) | ||
| Pathologic T category | <0.001 | <0.001 | |||||
| pT1-T2 | 114 (62.3) | 109 (66.9) | 5 (25.0) | 99 (75.6) | 15 (28.8) | ||
| pT3-T4 | 69 (37.7) | 54 (33.1) | 15 (75.0) | 32 (24.4) | 37 (71.2) | ||
| Pathologic N category | 0.023 | <0.001 | |||||
| pN0 | 125 (68.3) | 116 (71.2) | 9 (45.0) | 102 (77.9) | 23 (44.2) | ||
| pN1-3 | 58 (31.7) | 47 (28.8) | 11 (55.0) | 29 (22.1) | 29 (55.8) | ||
| Pathologic stage | <0.001 | <0.001 | |||||
| I | 99 (54.1) | 95 (58.3) | 4 (20.0) | 86 (85.6) | 13 (25.0) | ||
| II | 55 (30.1) | 48 (29.4) | 7 (35.0) | 34 (26.0) | 21 (40.4) | ||
| III | 29 (15.8) | 20 (12.3) | 9 (45.0) | 11 (8.4) | 18 (34.6) | ||
| Lymphovascular invasion | 0.002 | 0.001 | |||||
| Negative | 130 (71.0) | 122 (74.8) | 8 (40.0) | 102 (78.5) | 28 (52.8) | ||
| Positive | 53 (29.0) | 41 (25.2) | 12 (60.0) | 28 (21.5) | 25 (47.2) | ||
| Venous invasion | 0.001 | 0.008 | |||||
| Negative | 177 (96.7) | 161 (98.8) | 16 (80.0) | 129 (99.2) | 48 (90.6) | ||
| Positive | 6 (3.3) | 2 (1.2) | 4 (20.0) | 1 (0.8) | 5 (9.4) | ||
| Perineural invasion | <0.001 | 0.047 | |||||
| Negative | 160 (87.4) | 149 (91.4) | 11 (55.0) | 118 (90.8) | 42 (79.2) | ||
| Positive | 23 (12.6) | 14 (8.6) | 9 (45.0) | 12 (9.2) | 11 (20.8) | ||
a Early gastric carcinoma;
b Advanced gastric carcinoma.