Table 2.
Frailty and geriatric assessment measures (N = 48a).
| Mean ± SD | % impaired | |
|---|---|---|
| Fried Frailty Index (FFI) | 1.8 ± 1.2 | 27.1 |
| Weight loss >10 pounds in past year | 47.9 | |
| Self-reported exhaustion | 36.2 | |
| Low self-reported physical activity | 45.8 | |
| Slow gait speed | 21.7 | |
| Low grip strength | 31.3 | |
| Frailty score | ||
| 0 | 15.6 | |
| 1 | 24.4 | |
| 2 | 33.3 | |
| 3 | 17.8 | |
| 4 | 8.9 | |
| Geriatric assessment (GA) | ||
| MOS physical (<75 indicates impairment) | 66.0 ± 25.7 | 54 |
| Impairment in IADL (<14 indicates impairment) | 13.2 ± 1.6 | 31.3 |
| KPS physician rated (<80 indicates impairment) | 82.1 ± 9.2 | 14.6 |
| KPS patient rated (<80 indicates impairment) | 83.8 ± 11.9 | 19.2 |
| Timed up and go | 11.4 ± 3.1 | 50 |
| Falls in past 6 months (≥1 fall indicates impairment) | 0.38 ± 1.3 | 14.6 |
| Comorbidity (Physical Health Subscale, >3 indicates impairment) | 2.4 ± 1.7 | 27.1 |
| Cognition (Blessed Orientation Memory Concentration Test, ≥11indicates impairment) | 3.6 ± 5.0 | 6.3 |
| CES-D≥16 | 15.1 ± 9.0 | 38.3 |
| MOS Social Activity Limitations | 52.8 ± 19.6 | N/A |
| MOS Social Support Survey | 88.9 ± 15.2 | N/A |
| Self-reported weight loss | 5.5 ± 6.9 | 54.2 |
| GA toxicity risk score | ||
| Age ≥ 72 | 7.3 ± 2.3 | 35.4 |
| Hemoglobin | 8.3 | |
| Creatinine clearance | 4.2 | |
| Hearing impairment | 31.3 | |
| Falls in past 6 months | 14.6 | |
| Assistance with medications | 6.3 | |
| Limitation in walking 1 block | 31.3 | |
| Decreased social activity | 41.7 |
Legend: MOS = Medical Outcomes Survey; IADL = Instrumental Activities in Daily Living; KPS = Karnofsky Performance Score; CES-D = Center for Epidemiological Studies-Depression; CARG = Cancer and Aging Research Group; GA = geriatric assessment.
a
All measures were obtained in 48 subjects except for the following due to missing data: FFI index = 45; self reported exhaustion N = 47; gait speed N = 46; Frailty Score N = 45; KPS patient rated N = 47, Time up and go N = 46; CES-D N = 47; MOS Social Activity N = 47; Self-reported weight loss N = 47.