. Author manuscript; available in PMC: 2019 Oct 9.

Published in final edited form as: J Geriatr Oncol. 2018 Jul 10;10(1):48–54. doi: 10.1016/j.jgo.2018.06.007

Table 4.

Multivariate models evaluating the association between patient characteristics and treatment-related grade 3–5 toxicity during first cycle chemotherapy.

Predictor variable	Odds ratio (OR)	95% confidence interval (CI)
Model 1(AIC = 55.1, c = 0.84)
Frail (FFI ≥ 3)	7.03	1.11–44.55
Age (per year)	1.14	1.03–1.27
BSA (per SD)	3.87	1.49–10.07
Comorbidty score (per unit)	1.48	0.93–2.36
Model 2 (AIC = 62.9, c = 0.77)
GA toxicity risk score (>7)	4.26	1.03–17.65
Comorbidity Score (per unit)	1.53	1.01–2.32
BSA (per SD)	2.25	1.13–4.47
Model 3 (AIC = 60.1, c = 0.81)
Frail (FFI ≥ 3)	5.82	1.06–31.81
GA toxicity risk score > 7	3.75	0.85–16.53
Comorbidity Score (per unit)	1.57	1.01–2.45
BSA (per SD)	2.52	1.21–5.28

Legend: FFI=Fried Frailty Index; BSA = body surface area; SD = standard deviation; GA = geriatric assessment, c = c-statistic.