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. Author manuscript; available in PMC: 2020 Jun 19.
Published in final edited form as: Nature. 2019 Jun 19;570(7762):514–518. doi: 10.1038/s41586-019-1310-4

Extended Data Table 2 |.

Results of the meta-analysis

Height1 BMI2
Analysis known
loci3 		novel
loci4 		novel,
shared5 		novel,
unshared6 		known3 novel4 novel,
shared5 		novel,
unshared6
GIANT-only GWAS 425 0 74 0
PAGE-only GWAS 46 8 9 0
UKB50k-only GWAS 91 1 8 2
GIANT+PAGE meta 4057 82 37 647 38 31
45 7
GIANT+UKB50k meta 4127 107 62 677 28 21
1

Meta-analysis with previously reported height data24.

2

Meta-analysis with previously reported BMI data23.

3

Known loci include only the 425 height loci and 74 BMI loci from GIANT.

4

Novel loci were identified as P > 5 × 10−8 in the GIANT-only dataset and P > 5 × 10−8 in the specified analyses.

5

Novel, shared loci were identified as P > 5 × 10−9 in both GIANT+PAGE and GIANT+UKB50k datasets.

6

Novel, unshared loci were identified as P > 5 × 10−9 in either GIANT+PAGE or GIANT+UKB50k, but not in both datasets.

7

A modest number of known loci were significant in the GIANT-only GWAS, but not in the meta-analyses. These known loci were still included in PVE calculations.