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. Author manuscript; available in PMC: 2019 Oct 9.
Published in final edited form as: ACS Chem Neurosci. 2019 Aug 20;10(9):4160–4182. doi: 10.1021/acschemneuro.9b00410

Figure 1.

Figure 1.

Iterative strategy for generating novel noncatechol analogues of compound 1 with increased agonist activity at D1R and diverse functional selectivity profiles.