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. Author manuscript; available in PMC: 2019 Oct 9.
Published in final edited form as: Wiley Interdiscip Rev Dev Biol. 2018 Feb 13;7(3):e312. doi: 10.1002/wdev.312

Figure 1:

Figure 1:

Primitive hematopoiesis in zebrafish is responsible for generating the first populations of erythroid and myeloid cells. (A) Camera lucida drawing with superimposed green coloring depicting expression of an ETS transcription factor in the anterior (arrowhead) and posterior (arrows) lateral plate mesoderm. Primitive blood lineages are specified in anterior and posterior lateral plate mesoderm during early somitogenenesis. (B) Confocal image of a 16 hour-old Tg(fli1a:egfp)y1 embryo showing transgenic expression of EGFP in the anterior (arrowhead) and posterior (arrows) lateral plate mesoderm. (C) Camera lucida drawing of a 31 hpf zebrafish embryo with a blue box noting the approximate region of the trunk shown in panel D. (D) Double in situ hybridization staining for hbae1.1 primitive erythrocytes (red, arrows) and cmyb developing HSPCs (blue, arrowheads) in the ventral floor of the dorsal aorta of 32 hpf embryo.